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We have established that CO2 is effectively an acid. Let us be sure we understand why normal metabolic production of CO2 does not keep acidifying the body. An enormous of amount of CO2 is generated from metabolism each day. It is produced in our body at a rate of about 9 mmol/min. However, it is eliminated at the same rate, so there is no net addition. As arterial blood flows into tissue capillaries the majority of the CO2 entering the blood immediately combines with water to form hydrogen ions and bicarbonate, catalyzed by carbonic acid in red blood cells. Most of the hydrogen ions then combine with non-bicarbonate buffers (eg, hemoglobin), so the change in pH is not great, although there is a small decrease. The concentration of bicarbonate rises by about 1 mmol/L (from 24 to 25 mmol/L). When this blood carrying the newly loaded CO2 (now venous blood) reaches the capillaries of the lungs, the processes that occurred in the tissue capillaries are reversed. Bicarbonate and hydrogen ions combine to generate CO2 and water, and the CO2 diffuses into the air spaces of the lungs. The pH rises a little, and the concentration of bicarbonate falls by about 1 mmol/L (back to 24 mmol/L). asp.net mvc barcode generator Free Barcode API for . NET - Stack Overflow Could the Barcode Rendering Framework at Codeplex GitHub be of help? ...There is a "3 of 9" control on CodeProject: Barcode . NET Control . generate barcode in asp.net using c# How to create and display a BarCode in a web ... - DevExpress 22 Dec 2015 ... This example illustrates how you can use our new Bar Code Library in ASP . 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Once the osmolality of the luminal fluid approaches that of the interstitial fluid, the cortical collecting duct then behaves analogously to the proximal tubule, reabsorbing approximately equal proportions of solute (mainly sodium chloride) and water The result is that the tubular fluid, which leaves the cortical collecting duct to enter the medullary collecting duct, is iso-osmotic compared with cortical plasma, and its volume is greatly reduced compared with the amount entering from the distal tubule In the medullary collecting duct, solute reabsorption continues but water reabsorption is proportionally even greater In other words, the tubular fluid becomes more and more hyperosmotic and reduced in volume in its passage through the medullary collecting ducts because the interstitial fluid of the medulla is very hyperosmotic, for reasons discussed later. 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How does ADH convert epithelial water permeability from very low to very high An alternative name for ADH is vasopressin, because the hormone can constrict arterioles and thus increase arterial blood pressure, but ADH s major renal effect is antidiuresis (ie, against a high urine volume ) In the absence of ADH, the water permeability of the cortical and outer medullary collecting duct is very low, and little if any water is reabsorbed from these segments, resulting in water diuresis On the other hand, in the presence of high plasma concentrations of ADH, the water permeability of all regions of the collecting ducts is great, and only a small volume of maximally hyperosmotic urine is excreted. The tubular response to ADH is not all or none, however, but shows graded increases as the plasma concentration of ADH is increased over a certain range, thus permitting fine adjustments of collecting-duct water permeability and, hence, water reabsorption (The control of ADH secretion is described in 7) ADH acts in the collecting ducts on the principal cells, the same cells that reabsorb sodium (and, as is seen in 8, secrete potassium) The renal receptors for ADH (vasopressin type 2 receptors) are in the basolateral membrane of the principal cells and are different from the vascular receptors (vasopressin type 1) The binding of ADH by its receptors results in the activation of adenylate cyclase, which catalyzes the intracellular production of cyclic adenosine monophosphate This second messenger then induces, by a sequence of events, the migration of intracellular vesicles to, and their fusion with, the luminal membrane. generate barcode in asp.net using c# . 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